Osmolarity regulation in body fluids

  1. Recognize the relationship between antidiuretic hormone (ADH) level and Urine osmolality (Uosm), Total solute excretion and urine flow rate (V)
  2. Describe how changes in osmolality and vascular pressure activates the ADH secretion
  3. Recognize why the ADH release is more sensitive to the osmotic than the hemodynamic control
  4. Identify how baroreceptors modulates the osmotic control in the ADH release
  5. Describe the renal mechanism for dilution of the urine
  6. Describe the renal mechanism for concentration of the urine
  7. Describe Free Water Clearance (CH2O) concept
  8. Calculate Free Water Clearance (CH2O)