Tubular transport of sodium and water

  1. Describe how filtered load of water and sodium are almost completely reabsorbed in a water balanced subject
  2. Describe the secretion/reabsorption of Urea and Potassium (K+) in a water balanced subject
  3. Describe the transcellular and paracellular transport of substances
  4. Recognize the functional differences among the Apical and Basolateral membranes of the tubular cells
  5. Recognize the importance of the Na+– K+ pump in the basolateral membrane of the tubular cells
  6. Describe the percent of Na+ reabsorption along each segment of the nephron
  7. Describe the mechanisms involving sodium transport along the tubular segments of the nephron
  8. Recognize the hormonal action in the transport of Na+ in the DT and cortical CD
  9. Describe the percent of Water reabsorption along the PT, DLH, CD segments of the nephron
  10. Recognize the hormonal action of the transport of water along the CD
  11. Recognize Na+ reabsorption with Bicarbonate, Glucose, aa, lactate, and Pi transport in the first half of proximal tubule
  12. Recognize Na+ reabsorption with Cl–, in the second half of proximal tubule
  13. Compare the solute (Na+, Cl–, Pi, HCO3–, Glucose, aa, Lactate) concentration along the proximal tubule
  14. Describe the mechanism of Na+ reabsorption in the thick ascending limb of Henle’s loop (TAHL)
  15. Describe the mechanism of water reabsorption in the descending limb of Henle’s loop (DLHL)
  16. Describe the differences among the transcellular (Na+– K+– Cl–) transport and paracellular (Na+, K+, Ca++, Mg++) transport
  17. Describe the Na-transport in the early segment of the distal tubule that produce dilution of the “pre-urine”
  18. Describe the Na-transport in the late segment of the distal tubule and cortical collecting duct
  19. Describe the functional difference among Principal and Intercalated Cells